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High Quality Ampicillin Trihydrate & Amoxicillin Trihydrate

Basic Info

Model No.:  AMP

Product Description

Model NO.: AMP Certification: GMP Type: Chemical Reagent Volatile: Not Volatile Sample: Available Specification: GMP, BP/USP HS Code: 294110 Function: Antibiotic and Antimicrobial Agents Grade Standard: Medicine Grade State: Solid Color: White Trademark: Fraken Origin: China Amoxicillin Trihydrate
1. CAS No.: 61336-70-7
2. Standard: CP/EP/BP/USP
3. Content: 95-102%
4. Packing: 25kgs/drum


Amoxicillin is used in the treatment of a number of infections, including acute otitis media, streptococcal pharyngitis, pneumonia, skin infections, urinary tract infections, Salmonella infections, Lyme disease, and chlamydia infections. [3] It is also used to prevent bacterial endocarditis in high-risk people having dental work done, to prevent Streptococcus pneumoniae and other encapsulated bacterial infections in those without spleens, such as people with sickle-cell disease, and for both the prevention and the treatment of anthrax. [3] The United Kingdom recommends against its use for infectious endocarditis prophylaxis. [4] These recommendations have not appeared to have changed the rates of infection for infectious endocarditis. [5]


Amoxicillin Sodium


Ampicillin Trihydrate

1. CAS No.: 69-53-4
2. Standard: CP/EP/BP/USP/JP
3. Content: 95-102%
4. Packing: 25kgs/drum


Ampicillin is a beta-lactam antibiotic that has been used extensively to treat bacterial infections since 1961. Until the introduction of ampicillin by the British companyBeecham, penicillin therapies had only been effective against Gram-positive organisms such as staphylococci and streptococci. Ampicillin (originally branded as 'Penbritin') also demonstrated activity against Gram-negative organisms such as H. Influenzae, coliforms and Proteus spp. Ampicillin was the first of a number of so-called broad spectrum penicillins subsequently introduced by Beecham. Ampicillin is part of the aminopenicillin family and is roughly equivalent to its successor, amoxicillin in terms of spectrum and level of activity. [1] It can sometimes result in reactions that range in severity from a rash (in the case of patients that may unwittingly have mononucleosis) to potentially lethal allergic reactions such as anaphylaxis.


Ampicillin Sodium

Item
 

Specifications
 

Results
 

Characteristics
 

Appearance
 

A white or almost white powder and granule
 

A white granule
 

Identification
 

Infrared absorption spectrum
 

Infrared absorption spectrum accord with the reference spectrum of Amoxicillin Trihydrate
 

Meets the requirements
 

Tests
 

PH
 

3.5~5.5
 

4.8
 

Specific optical rotation
 

+290 ° ~ +315 °
 

+301 °
 

Related substances
 

Any impurity: ≤ 1.0%
 

Any impurity:0.3%
 

Dimethylaniline
 

≤ 20ppm
 

Never used in the production
 

Water
 

11.5~14.5%
 

12.8%
 

Sulphated ash
 

≤ 1.0%
 

0.1%
 

Assay
 

95.0~102.0% (C16H19N3O5S) calculated with reference to Anhydrous substance
 

98.9%
 

Bulk Density
 

0.59g/ml
 

Tapped Density
 

0.87g/ml
 

Particle size
 

84%,(20~80mesh)
 

Conclusion
 

The results conforms with BP2010 standards
 

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